Photobiomodulation with Led 627nm associated to resveratron in cutaneous injuries of rats: a double-blind controlled clinical study.

Authors

  • Patricia Pacheco Tyski Suckow
  • Ana Carolina Dorigoni Bini
  • Paulo Renato de Oliveira
  • Larissa Sakis Bernardi
  • Danillo Barbosa
  • Ivo Ilvan Kerppers
  • Alice Pansera
  • Gabriela de França Cury
  • Jaqueline Emiliano
  • Andressa Panegalli Hosni
  • Andressa Leticia Miri

DOI:

https://doi.org/10.17784/mtprehabjournal.2019.17.727

Abstract

Introduction: Drugs formulated as Resveratrol, associated with LED 627nm photobiomodulation, can increase the efficacy of active release, increased local circulation, cell proliferation and collagen synthesis, accelerating the healing process. Objective: To analyze the effects of 627nm LED photobiomodulation associated with Resveratrol on the tissue repair of induced wounds in Wistar rats. Methodology: We used 18 animals corresponding to the control groups, group LED 627nm with association to Resveratrol cream (GLed + Resv) 3 and 7 days. Results: Treatment with the use of LED associated with Resveratrol cream provided an efficient healing. In the statistical test, the significance level was observed between the groups of P <0.0156. In the multiple comparison between the pairs the Tukey’s test showed significance between the groups CG vs GLed627nm + Resv 7Day. Conclusion: The GLed + Resv group showed efficient inflammatory phase of healing, promoting a greater activation of fibroblasts and remodeling of the collagen fiber when compared to the control group.

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Published

2019-12-13

How to Cite

Suckow, P. P. T., Bini, A. C. D., Oliveira, P. R. de, Bernardi, L. S., Barbosa, D., Kerppers, I. I., … Miri, A. L. (2019). Photobiomodulation with Led 627nm associated to resveratron in cutaneous injuries of rats: a double-blind controlled clinical study. Manual Therapy, Posturology & Rehabilitation Journal, 1–5. https://doi.org/10.17784/mtprehabjournal.2019.17.727

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Section

Research articles